Abstract
The synthesis and structure-activity relationships of a series of novel phenoxyphenyl diamine derivatives with affinity for both the histamine H(3) receptor and the serotonin transporter is described.
MeSH terms
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Diamines / chemistry*
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Histamine Antagonists / chemical synthesis
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Histamine Antagonists / chemistry*
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Histamine Antagonists / pharmacology*
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Humans
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Molecular Structure
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Receptors, Histamine H3 / chemistry
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Receptors, Histamine H3 / drug effects*
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Selective Serotonin Reuptake Inhibitors / chemical synthesis
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Selective Serotonin Reuptake Inhibitors / chemistry*
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Selective Serotonin Reuptake Inhibitors / pharmacology*
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Structure-Activity Relationship
Substances
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Diamines
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Histamine Antagonists
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Receptors, Histamine H3
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Serotonin Uptake Inhibitors